Tag: 上海楼凤

Audi teases sharp AIme design study for Shanghai Motor Show

first_img 0 2018 Audi S4: The sweet spot sport sedan More From Roadshow Concept Cars Autonomous Vehicles Electric Cars Audi’s tradition of incorporating “AI” into the names of its futuristic concepts will continue at the 2019 Shanghai Motor Show, with the addition of the AI:me design study.Audi on Tuesday released a set of teaser sketches for the AI:me design study concept, ahead of its debut at the 2019 Shanghai Motor Show on April 15. Audi didn’t offer up too many details, saying only that it shows off Audi’s idea of an automated car for “the megacities of tomorrow.”Its intended purpose is evident in its design. The wheels are stretched as far to the extremes of the body as possible, both longitudinally and latitudinally, leaving oodles of space for its occupants. It doesn’t stray too far from Audi’s design language, though, retaining some semblance of a grille and a set of headlights that look like they could have come from any recent Audi concept.Enlarge ImageThe grille is a dead giveaway that it’s an Audi. But the rest of it? Not so much. Audi There’s a retractable steering wheel inside with a futuristic design that’s closer to an aviation yoke than a traditional steering wheel. Audi made generous use of wood in the cockpit, and it’s offset with leather and other materials, in addition to a series of small screens integrated in the door panels. Looking forward, there’s a single screen that seems to occupy nearly the entire width of the dashboard.Audi’s “AI” concepts are all pretty wild in different ways. The Aicon concept was a wildly styled autonomous EV with 500 miles of range and its own drone, and it did away with traditional headlights and taillights. And then there’s the spongeworthy Elaine concept, which relied a little less on autonomy and carried a more traditiona shape akin to Audi’s Sportback crossovers.audi-aime-teaser-003Enlarge ImageIf only interesting steering wheels were able to graduate to production. Silly regulations… Audi 2018 Audi Q7: Rockin’ the suburbs More about 2019 Audi Q8 Post a comment Tags Review • 2019 Audi Q8 review: Stop worrying and love the roof Share your voice Preview • 2019 Audi Q8: Cross-country tech titan Shanghai Motor Show 2019 Audi Audi 2019 Audi Q8 review: Stop worrying and love the rooflast_img read more

Amazon Echo Dot Kids Edition promises an ageappropriate Alexa

first_imgAmazon has a new Alexa speaker, the Echo Dot Kids Edition. Amazon Amazon updated its Echo Dot speaker back in 2018, so it’s no surprise that the tech company decided to revamp its original Echo Dot Kids Edition with a next-gen device as well. At a glance, Amazon clearly drew inspiration from the third-generation Echo Dot, which has a more rounded shape, complete with mesh fabric and a few color options. The new Echo Dot Kids Edition costs $70 (Amazon says it will be on sale for $50 for “a limited time”) and comes in rainbow (pictured above) and “frost blue” color finishes. See it at AmazonNote that CNET may get a share of the revenue if you buy anything featured on our site.Amazon says the new Echo Dot Kids Edition is “70% louder” than the first-gen version and includes a year of FreeTime Unlimited. FreeTime Unlimited is a subscription service that offers Alexa features just for kids — and provides controls for parents, as well as a variety of non-Echo features on Fire tablets and other devices for children. Which Amazon Echo speaker should you buy? Amazon’s new Alexa features put more emphasis on privacy Pre-Prime Day deal: The Amazon Echo is only $65 But what about your kid’s privacy? Amazon has recently come under fire following reports that the company holds on to transcripts of your Alexa conversations, even after you’ve deleted the audio clip. Amazon has since introduced new features, such as the  “Alexa, delete everything I said today” command. Child advocacy groups also have issues with the first-generation Echo Dot Kids Edition, according to a report in May claiming that the speaker violates privacy laws, prompting a request for an investigation by the Federal Trade Commission. Amazon recently introduced the Echo Show 5 as well, which is scheduled for a June 26 release. The Echo Show 5 is a smaller smart display with a 5.5-inch screen and a built-in privacy screen. It doesn’t have kid-specific features, but you might want to get a full sense of what’s on the horizon for Echo devices before you buy. Read more about Alexa privacy.The new Echo Dot Kids Edition is available for preorder now and is expected to ship later this month. Read more: Which Amazon Echo speaker should you buy? 1:58 Further reading Smart Speakers & Displays Wireless & Bluetooth Speakers All of Amazon’s Alexa smart speakers reading • Amazon launches new Alexa device for kids but privacy issues will still scare some parents Kids try to stump Alexa Aug 31 • Best smart light bulbs for 2019 (plus switches, light strips, accessories and more) Tags Share your voice 0 15 Photoscenter_img Aug 31 • Alexa can tell you if someone breaks into your house Post a comment Aug 30 • iRobot Roomba S9 Plus vs. Neato Botvac D7 Connected • See All CNET Smart Home Best laptops for college students: We’ve got an affordable laptop for every student. Best live TV streaming services: Ditch your cable company but keep the live channels and DVR. Aug 30 • Battling bot vacs: iRobot Roomba S9+ vs Neato Botvac D7 Connected Examples of Alexa skills only available via FreeTime Unlimited include Disney Dance Floor by Disney Publishing, Baby Shark Adventures by Pinkfong and Ghostbusters by Sony.New FreeTime Unlimited Alexa features include news reports via National Geographic and News-o-Matic with the command, “Alexa, what’s my news?” Alexa Skill Blueprints is also new. With Blueprints, parents and kids can “build an interactive adventure story” from an existing template and more.The FreeTime Unlimited parental controls service will cost Amazon Prime customers $3 per month. Without Prime, the service costs $5 per month.  CNET Smart Home Now playing: Watch this: Alexa Amazonlast_img read more

Can Indian opener KL Rahul break Pakistani cricketer Babar Azams record in

first_imgPandya and Rahul in England.Gareth Copley/Getty ImagesIndian opener KL Rahul is on the verge of achieving a milestone of becoming the fastest to score 1000 runs in T20Is and breaking Pakistani cricketer Babar Azam’s record when Team India face West Indies on Saturday, August 3. Azam achieved this feat in 26 innings.The part-time wicket-keeper and frontline batsman, who is quite comfortable in this format of the game, is just 121 runs short of becoming the seventh Indian to score 1000 runs in T20 internationals. If he scores the required number of runs in Saturday’s clash, then he will break the record of Babar Azam as he will achieve the feat in 25 innings. Indian skipper Virat Kohli reached the milestone after playing 27 innings also.It is not an easy task for the Karnataka born player as scoring a ton in a T20 match is never easy. But the 27-years old right-hander already has three centuries in T20 matches out of which two have been scored for Team India.But, looking at his current form, it will not be that easy for the opener to play such a massive innings. He was in mixed form through the ICC Cricket World Cup 2019. Rahul got starts in many of the matches but failed to convert them to big scores except on one occassion when he scored a century against Sri Lanka. Team India sporting the special cap. Robert Cianflone/Getty ImagesIndia exited the World Cup after facing defeat at the hands of New Zealand by 18 runs. After India’s return, a lot of controversies surrounding the team started to come up and the coaching staff were also given an extension till the end of the West Indies series. BCCI has already accepted applications for the posts in the coaching unit.Currently, the Men in Blue have gone to play three ODIs and T20Is and two Test matches against the West Indies in the Caribbean. The Test matches will be the part of ICC World Test Championshiplast_img read more

Archeologists unearth King David era temple near Jerusalem

first_imgFigurines of a person. Photograph: Clara Amit, courtesy of the Israel Antiquities Authority Explore further Citation: Archeologists unearth King David era temple near Jerusalem (2012, December 28) retrieved 18 August 2019 from https://phys.org/news/2012-12-archeologists-unearth-king-david-era.html The temple was discovered as part of a dig at a site known as Tel Motza, after the city of Mozah mentioned in the Old Testament. The site was first uncovered as construction began on what was to be a new freeway between Jerusalem and Tel Aviv back in the 90’s. Since that time most researchers had concluded that the ancient community was little more than a storage facility for grain used by people in Jerusalem. This new find suggests however, that the settlement was more than that.At the time that the temple was in use, a period during the King David era, the First Temple, in Jerusalem had already been built, and worshippers had been instructed to use it instead of other facilities to discourage the worship of various idols. Artifacts found inside the temple show that the people who visited the temple had chosen to ignore the decree and instead continued to idolize their icons as they chose. What’s surprising, the researchers note, is how close the temple, and hence the ongoing idol worshiping practices, were to Jerusalem – close enough to walk. (Phys.org)—Israel’s Antiquities Authority (IAA) has announced that archeologists have unearthed a temple within walking distance of Jerusalem that appears to be approximately 2,750 years old. Artifacts found inside the temple suggest that despite the ban on idol worship at the time, those who visited the temple continued to engage in such practices. Figurine of a horse. Photograph: Clara Amit, courtesy of the Israel Antiquities Authoritycenter_img Ancient seal found in Jerusalem linked to ritual © 2012 Phys.org The newly discovered temple has exceptionally thick walls and is situated facing towards the east, to take advantage of the rising sun – its rays would have illuminated the objects that sat inside the temple, a clear attempt to glorify them. The temple also had what the researchers believe was once an alter in the courtyard along with a host of sacred vessels – pottery fragments and pieces of chalices – likely used for ceremonial purposes.The discovery of the temple has historians excited because very few of them from that era have survived to modern times. Also, notably, researchers have found figurines inside the temple, representing animals – and some human – that hint, they say, of a coastal Philistine influence. They note that much more research will have to be undertaken before an accurate picture of the temple and surrounding area can be made. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

The Himalayan expedition

first_imgCascading waterfalls, mighty mountains, wild forests and the lush green valleys  make for everyone’s idea of utopia. For some it is a reality that they breathe day in and day out. The Himalayas, nurtures and sustains the faiths and socio-religious beliefs of its civilization. It cradles myths, legends and tales – some told some untold. Author Alka Raghuvanshi and photographer Sanjay Sharma capture these magical moments in places few have ventured due to reasons of inaccessibility in the book Also Read – ‘Playing Jojo was emotionally exhausting’ Garhwal Himalayas- Chorus of Solitude. ‘Perhaps it was ordained that many of the trips were made well before the book was even envisaged. And as the reader goes through the maze of legends and reality juxtaposed in weird and wonderful patterns, it would be important to remember that this journey into the unforgiving terrain – one wrong move is all that separates life from life eternal,’ says the author Alka Raghuvanshi. The photographer made endless trips to most places featured in this book in different seasons in his quest for getting just the right picture, including earlier this year in adverse weather conditions. Being the last documentation of the Uttrakhand region before havoc, this book written over six years assumes even more importance in this context.last_img read more

Lightning strikes kill 13 leave 20 others injured

first_imgKolkata: As many as 13 people were killed and 20 others injured in lightning strikes in various parts of the state on Monday morning.A nor’wester lashed different districts, accompanied by lightning, resulting in death of the victims, who were mostly farmers. They were working in the fields when the accident occurred.Among the deceased, three persons were from Murshidabad, Nadia and North 24-Parganas each, while four others were from Dakshin Dinajpur and Malda, two each from each district. Also Read – Heavy rain hits traffic, flightsAccording to a senior official of the disaster management department, most of the victims were out on streets or fields, when they were struck by lightning. It has been learnt that among the injured, four persons from Purulia are stated to be in critical condition.In view of the warnings issued by the weather office, the district administrations have alerted all the blocks, asking them to take precautionary measures so that such incidents can be averted. The villagers in various blocks have been asked not to work out on the field during a thundershower. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedSeveral parts of South Bengal districts remained overcast from the early Monday morning. There was heavy downpour in the districts of Birbhum, Bankura, East and West Burdwan, Jhargram and Midnapore. The city and its adjoining areas in North and South Bengal also received rainfall on Monday morning. No damage or casualty has however been reported from the city.According to the weather office, a wind measuring around 60 km/h hit various districts, along with the rain bringing down the temperature by a few notches. People from the city have also breathed a sigh of relief, after respite from the sultry and uncomfortable weather. The commuters in the city and suburban areas also faced difficulties in reaching their destinations due to rain accompanied by storm. The regional meteorological centre at Alipore has predicted thundershower in the South Bengal districts in the next 48 hours.Heavy rain and storm have affected train services in various sections of Howrah and Sealdah divisions of Eastern Railway on Monday morning. Many of the local trains were delayed due to safety precautions.Train services on the Krishnanagar-Lalgola section were affected since 9.33 am, as some debris fell on the overhead wire at Bethuadahari. As a result of the incident, 13113 UP Kolkata-lalgola Hazarduari Express was detained near Bethuadahari. A tower van was pressed into action for the restoration of train services in the section.last_img read more

IntelliJ IDEA 20183 is out with support for Java 12 accessibility improvements

first_imgYesterday, the JetBrains community announced IntelliJ IDEA 2018.3, this year’s third major update. The IntelliJ IDEA 2018.3 is a massive new update that delivers Java 12 support, Multiline TODO comments, GitHub Pull Requests, Git submodules, Accessibility improvements, and more. Major updates in the IntelliJ IDEA 2018.3 Java Updates Support for Java 12: The 2018.3 version adds an initial support for the upcoming Java 12. Users can preview the Raw String Literals (JEP 326) in the IDE. Quickly spot duplicates: Users can now quickly spot duplicates in more complicated cases using this IDE. Java Stream API improvements: Redundant sorted calls made before the subsequent min call are now easily detected. New data-flow-based inspection: The new inspection known as ‘Condition is covered by further condition’ detects situations where the first condition is unnecessary as it’s covered by the second one. The new IDE provides a quick-fix to remove such redundant conditions. Detection of redundant usages of the @SuppressWarning annotation: The IDE now identifies situations where a suppressed inspection no longer addresses any warnings in the associated method body, class, or statement. Editor Updates Issues in code are highlighted: The IDE highlights the first and all subsequent TODO comment lines in the editor and displays them in the TODO tool window. New indentation status bar: A new indentation status bar displays the size of the indent in the current file. Improvements in the EditorConfig support: You can create a scope to disable code formatting from being done on specific files and folders. Go to the ‘Formatter Control’ tab in Preferences / Settings | Editor | Code Style. Syntax highlighting and code completion are now available for EditorConfig files. Version Control Updates Initial support for GitHub Pull Requests:  With this users can now view PRs in their IDE. Support for Git submodules: update your project, commit changes, view diffs, and resolve conflicts. New GitHub Pull Requests tool window: With this tool window, users can preview all the pull requests in your GitHub repository. Advanced navigation in VCS Log: Users can use the Forward and Back navigation actions while they are in the VCS Log after they navigate from the commit hashes to the commit in the VCS Log tab, or after they use the Go to hash/branch/tag action. Simply use the left and right arrow keys to navigate to the child or parent commit. Preview differences in the File History tab: Diff Preview is now available in the File History tab of the Version Control tool window. Kotlin Updates Kotlin 1.3 support: IntelliJ IDEA can help you migrate Kotlin project to Kotlin 1.3 and perform all the required changes in obsolete code to make it compliant with the latest state of the libraries. Enhancements in multiplatform project support: In Kotlin 1.3, the model of multiplatform projects has been completely reworked in order to improve expressiveness and flexibility, and to make sharing common code easier. IntelliJ IDEA provides a set of project examples that cover the most common use cases. New Kotlin Inspections & Quick-fixes: Since the release of IntelliJ IDEA 2018.2, the Kotlin plugin has got over 30 new inspections, quick-fixes, and intentions that helps write a code much more effectively. Spring & Spring Boot Updates Spring Boot 2.1 support: IntelliJ IDEA 2018.3 fully supports Spring Boot 2.1. Configuration values annotated with @DataSize are validated using the default @DataSizeUnit if specified. Spring Initializr improvements: While creating a project using Spring Initializr, the IDE will suggest installing or enabling appropriate plugins to ensure that support for all selected technologies is present. Better JPA and Spring Data support for Kotlin: Now the IDE can automatically inject JPQL into query strings, providing completion for entity names and parameters. Users can write Spring Data interfaces in Kotlin, and IntelliJ IDEA will understand the entities used. The IDE provides smart completion for method names and quick-fixes for parameters. Maven Updates Users can now easily delegate all their build and run actions to Maven. They simply have to go to Preferences (Settings) | Build, Execution, Deployment | Build Tools | Maven | Runner and select the new Delegate IDE build/run actions to maven option. JVM Debugger Updates Attach to Java processes that were started without a debug agent:  After attaching to a process, users will be able to view the current thread’s state and variable values, and use the memory view. If users want to attach the debugger to their local process, they can use the handy new Attach Debugger action, which is available in the Run Tool Window Async stack traces in remote JVMs: IntelliJ IDEA 2018.3 now supports async stack traces in remote JVMs. To start using the agent remotely: copy /lib/rt/debugger-agent.jar to the remote machine.add -javaagent:debugger-agent.jar to the remote JVM options. Action to remove all breakpoints: IntelliJ IDEA 2018.3 comes with handy new actions that remove all the breakpoints in a project, or all the breakpoints in the file. JavaScript & TypeScript Updates Improved Angular support: This includes much more accurate code completion and Go to definition for variables, pipes and async pipes, and template reference variables. Autoimports in JavaScript: IntelliJ IDEA can now automatically add imports for symbols from the project’s dependencies, in JavaScript files. This works as long as there’s a TypeScript definition file inside the package, or the package contains sources written as ES module. Support for Node.js worker threads: Users can now debug Node.js workers in IntelliJ IDEA. Users should be cautious of using Node.js 10.12 or above and the experimental-worker flag. The IDE provides code completion for the worker threads’ API. Improved flexibility with ESLint and TSLint: Users can override severity levels from the linter’s configuration file and see all problems from the linter as errors or warnings. Kubernetes Update Support for Helm resource files: The IDE now resolves the Helm resource template files and provides with editing support, which includes code completion, rename refactoring, and inspections and quick-fixes. Navigation in Helm resource files: The IDE lets users navigate from a value’s usage to its declaration in the chart’s values.yaml file. Helm template result preview: The IDE can now preview the result of the Helm template rendering in the diff. Helm dependency update: A new Helm Dependency Update action is available to download the external tgz dependencies (or update the existing ones) and display them in the project tree. Database Updates Added support for Cassandra database: With this release, the team has added support for the NoSQL database, Cassandra. Improvements in SQL code completion: Now code completion works for: non-aggregated fields in GROUP BY, all the columns are listed in SELECT, MERGE, and INSERT INTO table variable, named parameters of stored procedures, numeric fields in SUM() and AVG(), FILTER (WHERE) clause, and field types in SQLite. Introduction to table alias: One can now use the Introduce table alias action to create an alias directly on the table, and this alias will automatically replace usages of the table’s name. Single connection mode: In IntelliJ IDEA 2018.3 users can view any temporary objects in the database tree. Also, it’s possible to use the same transaction in different consoles. To know more about these and other updates in detail, visit the JetBrains blog. Read Next IntelliJ IDEA 2018.3 Early Access Program is now open! What’s new in IntelliJ IDEA 2018.2 How to set up the Scala Plugin in IntelliJ IDE [Tutorial]last_img read more

Jeff Bewkes Time Warner CEO Jeff Bewkes neatly sid

first_imgJeff BewkesTime Warner CEO Jeff Bewkes neatly sidestepped questions about why he walked away from a merger with 21st Century yesterday, while Rupert Murdoch has offered his opinions on the episode.In a conference call with investors, Bewkes declined to comment directly on the Fox proposal, “except to say that the board and our senior management team appreciate the continued support of our shareholders”.This was in contrast to Fox chairman and CEO Murdoch, who said the decision to exit negotiations was “resolute” after Time Warner’s management and board refused to explore the “compelling offer”, and Fox’s share price dropped.“It became increasingly clear that the combination of the drop in our share price and the highly defensive nature of Time Warner’s actions was going to lead to a transaction where too much of the value created in success went to Time Warner shareholders,” added Murdoch’s second-in-command, Fox president and COO Chase Carey.He also defined the US$80 billion (€60 billion) proposal as “one of opportunity, not necessity or defensive concerns”, and said Fox had “no plans” to acquire any other content companies as an alternative.Though Bewkes declined to comment directly, he did outline some pitfalls of high-level media consolidation.“There are benefits and there are risks to making any kind of combination like that. There’s also the factor of business interruption, regulatory scrutiny and timings that comes into play,” he said.“I would just encourage everybody to look at all sides of the issue when you’re contemplating the benefits and the risks of putting very large companies together.”The combined Fox-Time Warner group would have included a channels stableincluding Fox, FX, TNT, HBO, Cartoon Network and truTV among others, along with the Fox and Warner Bros. Hollywood studios, and numerous broadcast, broadcast and distribution assets around the world.Bewkes comments came after the group posted improved year-on-year fourthquarter revenues of US$6.8 billion, with premium cable channel HBO singled out as a growth driver following a major recent content deal with on-demand platform Amazon Prime Instant Video.Fox, meanwhile, also posted growth in its Q4 results, up 17% on the same quarter in 2013. Its revenues were US$8.4 billion, though broadcast TV revenues fell 6% following a dip in advertising revenues for American Idol.last_img read more

Vivendi could strike a deal in the next few days t

first_imgVivendi could strike a deal in the next few days to end its legal dispute with Mediaset and forge a new content partnership involving Telecom Italia, according to press reports.According to Agefi-Dow Jones, citing an unnamed source, a three-way agreement involving Mediaset, Telecom Italia and either Vivendi or Canal+ is on the cards.A deal is expected before the next court hearing on Mediaset’s suit against Vivendi, which is scheduled for December 19.In an interview with Italian daily Corriere della Sera, Mediaset CEO Pier Silvio Berlusconi said that Telecom Italia had need of his company’s content, adding that it remained to be seen if “common interests” would overcome the “difficulties” between the pair.Berlusconi said that in any case Mediaset would continue to support its Mediaset Premium pay TV service, including an offer of Serie A Italian football. He said that Mediaset would participate in the next Serie A auction in a rational way, and added that the company was committed to continue to invest in series and movies.Telecom Italia recently confirmed that it was n talks with Mediaset about a new deal that would see it acquire Mediaset content to provide to subscribers of its Timvision subscribers.The TIM board approved by majority vote moves by the company’s management to finalise a “new and comprehensive multi-year agreement” with Mediaset to bring the latter’s linear channels, movies, TV series and sports news content to its platform. The agreement is envisaged coming into force from next year.last_img read more

The bull also made a comeback in 20092010 fighti

first_img The bull also made a comeback in 2009-2010, fighting its way up out of what seemed at the time to be the deepest hole (1.04) in October, 2008. Stocks have been on a long slide since the ratio last peaked at 3.24 in October, 2010, with the downturn in 2013 pushing multiples to previously unseen lows. No one—us included—has a crystal ball, and so it’s impossible to tell if the bottom is behind us. We can, however, gauge with certainty when an asset is cheap—and cash-generating companies selling for little more than book value are extraordinary values for big-picture investors. Now let’s see how these valuations look against the S&P 500. Gold stocks staged spring and summer rallies this year, but haven’t able to sustain the momentum. Many have sold off sharply in recent weeks, along with gold. That makes this a good time to examine the book value of gold equities; are they objectively cheap now, or not? By way of reminder, a price-to-book-value ratio (P/BV) shows the stock price in relation to the company’s book value, which is the theoretical value of a company’s assets minus liabilities. A stock is considered cheap when it’s trading at a historically low P/BV, and undervalued when it’s trading below book value. From the perspective of an investor, low price-to-book multiples imply opportunity and a margin of safety from potential declines in price. We analyzed the book values of all publicly traded primary gold producers with a market cap of $1 billion or more. The final list comprised 32 companies. We then charted book values from January 2, 2007 through last Thursday, October 15. Here’s what we found. At the current 1.20 times book value, gold stocks aren’t as cheap as they were when we ran the numbers in June, 2013, successfully pinpointing the all-time low of 0.91 (the turning point before the period in gray). Of course, that P/BV is hard to beat: it was one of the lowest values ever. And while the stocks not quite as cheap now, the valuation multiple still lingers close to its historical bottom. Remember, we’re talking about senior mining companies here—producers with real assets and cash flow selling for close to their book values. In short, yes, gold stocks are objectively selling cheaply. The juniors, of course, have been hit harder. It’s hard to put a meaningful book value on many of these “burning matches” with little more than hopes and geologists’ dreams, but valuations on many are scraping the bottom, making them even better bargains, albeit substantially riskier ones. What does this mean for us investors? It’s no surprise to see that every contraction in the ratio was followed by a major rally. In other words, the cure for low prices is low prices: The August, 2007 bottom (2.2) and the momentary downtrend that preceded it were quickly erased by a swift price rally leading to a January, 2008 peak (3.8).center_img Stocks listed in the S&P500 are currently more than twice as expensive as the gold producers. That’s not surprising given how volatile metals prices can be and how unloved mining is—but is it rational? Note that despite the downtrend in the last month, the multiple for the S&P500 remains close to a multiyear high. In other words, yes, the S&P 500 is expensive. This contrast points to an obvious opportunity in our sector. So is now the time to buy gold stocks? Answer: our stocks are good values now, and, if there is a larger correction ahead, they may well become fantastic values, briefly. Either way, value is value, on sale. As the most successful resource speculators have repeatedly said: you have to be a contrarian in this sector to be successful, buying low and selling high, and that takes courage based on solid convictions. Yes, it’s possible that valuations could fall further. However: The difference between prices and clear-cut value argue for going long and staying that way until multiples return to lofty levels again—which they’ve done every time, as the historical record shows. With a long-term time frame in mind, whatever happens in the short term is less of a concern. Building substantial positions at good prices in great companies in advance of what must transpire sooner or later is what successful speculation is all about. This is how Doug Casey, Rick Rule, and others have made their fortunes, and it’s why they’re buying in the market now, seeing market capitulation as one of the prime opportunities of the decade. That’s worth remembering, especially during a downturn that has even die-hard gold bugs giving up. Bottom line: “Blood in the streets” isn’t pretty, but it’s a good thing for those with the liquidity and courage to act. What to buy? That’s what we cover in BIG GOLD and the International Speculator. Thanks to our 3-month full money-back guarantee, you have nothing to lose and the potential for gains that only a true contrarian can expect.last_img read more

We are throwing good money after bad here as the

first_imgWe are throwing good money after bad here, as the The Washington Times reports: Roughly 6.5 million people with active Social Security numbers are age 112 and older, according to an audit by the Social Security Administration’s inspector general. The March 4 audit concluded that the administration “did not have controls in place to annotate death information” on the main electronic file… The inspector general said the questionable identification numbers put the government at risk of fraud and waste. Some of the numbers assigned to long-dead people were used fraudulently to open bank accounts, and thousands of numbers were apparently used by illegal immigrants to apply for work, CNS News reported. For all of its many shortcomings, the IRS does a darn good job of tracking who’s alive and who’s dead. Maybe it should send an intern over to the SSA to teach ’em how to cross out a name and number with a red pen. Until then, we’ll continue to lose money to people receiving benefits fraudulently and waste money tracking and prosecuting preventable identity-theft crimes. This is just one more example of why people protect their own money far better than any government agency ever will. After all, we all own red pens.last_img read more

first_img— 5:07: Wall Street Gets BLINDSIDED The 5:07 mark of this video is VERY CONTROVERSIAL. It’s no wonder Wall Street has sent out diversionary tactics on this strategy. They’ve been beaten at their own game! Click here to discover the shocking reveal at the 5:07 mark… and why it could help regular people collect $103K in the next 12 months. Bonner & Partners’ Exclusive One Week Only: Major Predictions Regarding Impending iPhone Launch Until midnight Wednesday, September 6th, the publishers at Bonner & Partners have organized a rare opportunity for you to get the behind-the-scenes story on what the new iPhone means for investors, before the official launch. They’ve arranged a top-level Silicon Valley insider – a former vice president at a key Apple supplier – to reveal four targeted iPhone plays that could make you between 414% and 2,100% over time, starting from September 6th. Hurry here to get the full scoop. Recommended Link Here’s why I’m telling you about this trend… Later this year, Apple will release the latest and most technologically advanced version of its most popular product: the iPhone 8. The iPhone 8 will almost certainly include wireless charging capabilities when it’s launched sometime this fall. Wireless power involves transmitting energy over radio frequency waves. It’s similar to wireless communications technology we use in our mobile devices. Behind the complex technology of wireless charging is something quite simple… The ability to charge your electronic devices without power cables. Imagine being able to come home after being out all day and placing your smartphone on your computer desk. That’s it. Nothing to plug in, no cables to worry about… Just set down the device, and it charges “magically.” This will be a game changer for Apple… and will likely boost iPhone sales. But I’m not writing today to tell you to buy Apple. You see, there’s a unique way to profit from Apple’s wireless trend… buying the companies that make the microchips Apple uses in its wireless devices. Following a Tech Giant Historically, Apple has used third-party chip providers for its wireless technology. Qualcomm has made chips for Apple’s cellular modems. And Broadcom has made Bluetooth and Wi-Fi chips for Apple. Broadcom is a good example of how profitable making chips for Apple can be. — Justin’s note: Today’s essay comes from my colleague Jeff Brown, editor of Exponential Tech Investor. Jeff has been working in the tech field for over two decades. He’s seeded over 70 private, early-stage tech companies… And he’s a formal advisor to eight tech startups.Right now, Apple’s iPhone 8 launch is on his radar… and he says you can profit from this big event. Read on to learn how (hint: It’s not by buying Apple)… By Jeff Brown, editor, Exponential Tech Investor In 2003, Apple introduced its first wireless mouse and keyboard. In 2010, Apple released its first external wireless computer trackpad. And in 2016, Apple removed the headphone jack from the iPhone 7. If you want to listen to music on the smartphone, you need wireless AirPods. As you can see in the graphic above, Apple is moving toward completely wireless technology. Recommended Link Apple released the iPhone 7 in September 2016. And Broadcom’s stock climbed 41% less than a year after the launch. Broadcom revenue from wireless chips sales came in at $1 billion in the third quarter of 2016. That was up 27% from the previous quarter. And the stock is up 50% since the iPhone 7 launch in September 2016. As you can see from the chart above, making chips for Apple’s signature phone can really boost business. Now, Apple is looking for chipmakers for its wireless charging feature. The company that lands this contract should see its stock push much higher. Tip of the Iceberg Some forecasts for Apple’s fourth-quarter 2017 iPhone shipments are coming in at around 90 million units. And each of them will likely carry a wireless charging chip. But Apple is just the tip of the iceberg. Since Apple released its very first iPhone in 2007, it’s been a trendsetter for other smartphone makers. Whatever new features Apple adds, others follow. And the rest of the mobile phone market is much larger than Apple’s shipment volumes. Samsung alone shipped 309 million smartphones in 2016… And Chinese company Huawei shipped 139 million. In 2016, Apple’s rivals shipped 1.27 billion smartphones. That’s a massive market for wireless charging chips. And wireless charging won’t be confined to just your mobile phone. Any electronic device will be a target for this technology. Wireless headphones, iPads, smartphones, health tracking devices like heart monitors, and even “smart clothes” will one day charge wirelessly… no power cables at all. You could even use this technology to continuously heat your morning cup of coffee so that it never gets cold. Companies I’m Watching Companies that make wireless charging chips will be big winners as this technology becomes the new reality. Here are a few on my radar: Analog Devices, Dialog Semiconductor, and Texas Instruments. If wireless charging is anywhere as successful as I think it will be, companies in this sector have the potential to see outsized returns. Regards, Jeff Brown Editor, Exponential Tech Investor P.S. As I mentioned, when Apple unveils its iPhone 8, I believe it will include wireless charging capabilities. But to pull this off, Apple will need the help of one company—a company that I’ve recently identified… That’s right—I’m confident that I have found the one company that will make Apple’s wireless charging feature a reality. And when Apple makes its announcement in the next few weeks, the price for this little-known, small-cap stock will skyrocket. Get all the details right here. In Case You Missed It… Doug Casey just released his newest novel. Drug Lord—Book 2 of the High Ground Novels—is now available on Amazon. In this riveting tale, Charles Knight returns to the United States after seven years traveling the world. He embarks on two concurrent professions: one as a major investor in a small pharmaceutical company, and the other as the head of a black market drug smuggling and distribution operation. Charles has to sort through the legal and illegal, moral and immoral, and right and wrong as he navigates the War on Drugs and the crony pharmaceutical industry. They all want him dead. But Charles intends to start a revolution. To get the whole story, you can order your copy of Drug Lord right here.last_img read more

When a relationship ends but love remains it can

first_imgWhen a relationship ends but love remains, it can be both frustrating and embarrassing.Dessa, a well-known rapper, singer and writer from Minneapolis, knows the feeling well. She’d spent years trying to get over an ex-boyfriend, but she was still stuck on him.”You’re not only suffering,” she says, “you’re just sort of ridiculous. Discipline and dedication are my strong suits — it really bothered me that, no matter how much effort I tried to expend in trying to solve this problem, I was stuck.”But things changed when Dessa turned to the frontiers of neuroscience for help. She came across a TED Talk by Helen Fisher, a biological anthropologist and visiting research associate at Rutgers University. Using a type of brain scan called functional MRI, or fMRI, Fisher had looked into the brains of love-struck people and noticed that certain parts of their brains were unusually active.”That you could objectively measure and observe ‘love’ — that had never occurred to me before,” Dessa says.She wondered: If science could map the sources of love in her brain, could it somehow make that love go away?The question led her to a controversial therapy technique called neurofeedback.The idea is simple: If you want to learn to lower your heart rate, it helps to be able to hear your pulse. And if you want to change patterns of brain activity, it might be helpful to be able to see what your brain is up to.One flavor of neurofeedback therapy uses a technology called electroencephalography (EEG). A cap full of electrical leads picks up brain waves and translates them into visual or audio cues — like shifting colors on a screen or a series of dings.The idea is that people can use this feedback to retrain those brain waves, changing underlying patterns in the process — turning down unwanted brain activity or turning up regions that are too quiet.Clinicians have used neurofeedback to try and treat all kinds of mental health issues: anxiety, depression, autism, and ADHD. And they say they’ve seen some positive results. Patients say they feel better.The growing popularity of EEG-neurofeedback has been met with skepticism. Some scientists say the power of this therapy may stem from the placebo effect. (They also point out that a lot of neurofeedback research is done by people who have a financial stake in the industry.)But more rigorous research from the past couple of years supports the idea that, at least in some cases, neurofeedback can be used to train the brain. Most of this research uses fMRI brain scans — not EEG — to peek inside the skull.In one study, participants learned to turn up a brain region linked to motivation and focus. In another, patients with depression were able to alleviate some of their symptoms. But scientists doing this research say there’s a lot of work to be done before it can be applied clinically.Could neurofeedback provide a balm for broken hearts? No research has been done in this area. But that didn’t stop Dessa from trying a sort of experiment on herself: nine EEG-neurofeedback sessions aimed at helping her brain escape the rut of romantic obsession.She says she felt different when she was done.”Before, I felt that I was really under the thumb of a fixation and a compulsion,” she says. “And now it feels like those feelings have been scaled down.”Now, maybe the neurofeedback had worked as practitioners suggest it does. Or maybe, alternatively, Dessa got the therapy she wanted in other ways — by talking through her experiment, by writing about it, by composing songs for her new album.Or maybe, her neurofeedback sessions helped her via the placebo effect. They suggested that her emotions are grounded in a physical organ — one that she might be able to influence. Maybe simply believing that she wasn’t helpless helped her change her mind and heal her heartbreak.Whatever the reason, Dessa is happy to begin to move on and to start a new chapter with her music.”I’ve written a bunch of sad rap bangers — I’d like to write other kinds of songs,” she says.Follow Skunk Bear, NPR’s science show, on YouTube and Facebook and please fill out our short survey so we can learn more about you and the kind of stories you’re interested in. Dessa’s new book, My Own Devices, was published Tuesday, Sept. 18. You can watch her perform behind NPR’s famous Tiny Desk here:Copyright 2018 NPR. To see more, visit http://www.npr.org/.last_img read more

American Airlines Glitch Caused It to Give Too Many Pilots Vacation Over

first_img Learn how to successfully navigate family business dynamics and build businesses that excel. Planning to fly with American Airlines this holiday season? We have some potentially bad news.According to Bloomberg, more than 15,000 American Airlines flights scheduled from Dec. 17 to Dec. 31 do not have a pilot, first officer or both due to a computer glitch that allowed too many staffers to take off for the holidays. The problem reportedly affects flights originating from Dallas Fort Worth International and other airports in Boston, Miami, New York, Philadelphia, Salt Lake City, and Charlotte, N.C.In a statement, American Airlines told PCMag it is “working diligently to address the issue” and it expects to “avoid cancellations this holiday season.””We have reserve pilots to help cover flying in December, and we are paying pilots who pick up certain open trips 150 percent of their hourly rate — as much as we are allowed to pay them per the contract,” the airline said. American said it will work with the Allied Pilots Association (APA) union to “take care” of its pilots and “ensure we get our customers to where they need to go over the holidays.”The computer glitch caused the airline’s scheduling system to show sufficient coverage for certain flights when that was not actually the case, Bloomberg reports. The airline has reportedly fixed the problem and believes its system is now working normally.The APA, meanwhile, isn’t happy with American’s proposed solution for crewing affected flights. The union has filed a grievance, saying the solution violates the company’s contract.”Because management unilaterally created their solution in violation of the contract, neither APA nor the contract can guarantee the promised payment of the premium being offered,” the union said in a statement. Add to Queue Angela Moscaritolo Next Article This story originally appeared on PCMag Thousands of flights scheduled from Dec. 17 to Dec. 31 do not have a pilot, first officer, or both due to a computer glitch that allowed too many staffers to take off for the holidays. Reporter American Airlines Glitch Caused It to Give Too Many Pilots Vacation Over Holidayscenter_img –shares Image credit: Shutterstock.com Register Now » Travel November 30, 2017 Free Webinar | July 31: Secrets to Running a Successful Family Business 2 min readlast_img read more

3 Ways Drone Startups Are Making Dangerous Workplaces Safer

first_img –shares Potential hazards such as loose scaffolding or fuel tank leaks are identified earlier. Free Webinar | July 31: Secrets to Running a Successful Family Business 3 Ways Drone Startups Are Making Dangerous Workplaces Safer Add to Queue Image credit: Hinterhaus Productions | Getty Images Technology Next Article Guest Writer Learn how to successfully navigate family business dynamics and build businesses that excel. Startup mentor, CEO and tech blogger If you look at the numbers on job-related accidents, something disturbing becomes clear — going to work can be unsafe.The International Labour Organization estimates that 2.3 million people worldwide die due to work-related reasons each year. It’s a figure that comprises both job-site accidents and deaths due to illness or exposure to hazardous materials. To put it in perspective, that is a million more deaths every year than the 1.25 million deaths, worldwide, attributed to road traffic.In high-risk industries such as construction the risk of death over a 45-year career is 1 in 200. Add to that the 340 million non-fatal workplace injuries that take place each year and it’s easy to see that we must find ways to reduce risks in work environments .Related: Amazon and Tesla Listed Among the Most Dangerous U.S. WorkplacesThe human toll should be enough to leave us motivated to effect change. But in every business, you also have to look at the bottom line, and workplace injuries and illnesses are costing employers more than $3 billion a year.As always, in technology we trust, and drones are part of the process of treating some of those problems. Whether at an oil refinery or a power plant, here are some of the ways drones are improving working conditions and respective drone startups that are part of the advancement.Inspection and collection.Keeping workers safe is a priority for all employers, and regular site inspections are an important component of this. But when it comes to inspecting hard-to-reach places, such as industrial chimneys, rooftops, fluid barrels, or even just a high scaffolding, often times it’s the inspection itself that causes injury. Some startups are aimed towards improving inspections, such as the Sparrow drone by Percepto. It’s an autonomous drone with day and night (thermal) vision capabilities, which treats safety at site inspections with its ability to access areas that would pose a danger to human inspectors. Without the risk to human life, the pre-programmed drone inspections can be performed more frequently. The result is that site inspectors are exposed to less harm, while potential hazards such as loose scaffolding or fuel tank leaks are identified earlier. Once the site is inspected, data needs to be collected. Drones are also able to collect, transmit and analyze site data more efficiently than humans can, giving employers a more accurate picture of what’s happening on their site.Related: 5 Ways Drones Are Changing the WorldEmergency situations.From fires to gas leaks to hazardous waste spills, disasters strike, even at the most diligently inspected work sites. Drones are minimizing the odds of a chemical disaster occurring, and they’re also acting as first-responders when the unimaginable happens. After all, there’s no reason to put human lives on the line, when you can send a drone in first to assess the situation.For the sake of evaluating an entire disaster site, drone company PrecisionHawk teamed up with the Environmental Protection Agency in 2014 to map out an industrial landfill in South Carolina that was releasing toxic particles into the air. The result was a full assessment of the area in under an hour, a job that would take human surveyors days or even weeks to complete, exposing them to unnecessary hazards.Security breaches.Whether industrial, military, or personal, perhaps one of the biggest uses for drones is in the area of security. While drones can’t replace their human counterparts or eliminate the need for manpower, there’s no question that a drone can cover more ground in less time than the combination of humans and stationary cameras.Aptonomy is a drone company which equips its UAVs with a night-vision camera. The low-flying drones can hone in on an intruder and capture a mugshot — something a stationary camera can do with less accuracy. But while it may seem that the benefits of security drones are mostly for employers, they also keep employees out of potentially dangerous situations. Because drones provide such an accurate picture in real time, they significantly reduce the risk posed to security guards and emergency responders.Related: The Drone Industry: Thoughts From an OutsiderWe still have a long way to go when it comes to keeping workers safe on the job. And while employers will never be able to achieve zero-risk on their sites, autonomous drones located on-site, conducting dozens of daily missions, are a huge step in the right direction to reducing exposure to hazardous materials, accidents and death. In the meantime, I’m grateful to be working from home today. 4 min read July 13, 2018 Yoav Vilner Register Now » Opinions expressed by Entrepreneur contributors are their own.last_img read more

Uber Is Giving Free Rides in This Town to Curb Drunk Driving

first_img Image credit: Pixabay Add to Queue Next Article Register Now » A New Jersey town on track for a record-breaking number of drunken driving cases has become the first U.S. municipality to partner with ride service app Uber to keep inebriated residents from getting behind the wheel.To keep the roads safe in Evesham Township, a town of 45,000 people in southern New Jersey, anyone drinking in at least 19 alcohol-serving establishments can now get a free ride home from Uber in a program funded by donors and started last week.Donations from area nonprofits and businesses are also funding a second free ride option that started on Friday: the mobile app BeMyDD, through which people can hire a driver to get both them and their car home.”We’re dealing with people who might’ve had too much to drink, so we needed to make it so easy for them to open their iPhone and push a button,” Evesham Mayor Randy Brown said.Evesham had been on track to reach 250 DUI arrests in 2015, a record for the town, Brown said.The effort extends a pilot program tested during September, when town shuttles provided free rides to more than 350 people. The shuttles helped decrease DUI arrests to eight in September from a monthly average of 23 from January to August, a drop of 65 percent, Brown said.Free rides are available from the designated bars and restaurants from 9 p.m. to 2 a.m. every night of the week. The partnership with both apps runs through Jan. 2.”We began working with Mayor Brown through our national partner, Mothers Against Drunk Driving, and realized it was the perfect opportunity to use our technology to help take drunk drivers off the road,” Ana Mahony, general manager for Uber New Jersey, said in a statement.Uber is testing the pilot locally and is considering working with other towns to create a similar partnership, a spokesman for the company said.Alexa Milkovich, vice president of marketing for BeMyDD, said the company recruited drivers quickly to make sure the area would have enough to meet demand.(Reporting by Katie Reilly) Uber Reuters October 23, 2015center_img 2 min read Learn how to successfully navigate family business dynamics and build businesses that excel. –shares Free Webinar | July 31: Secrets to Running a Successful Family Business This story originally appeared on Reuters Uber Is Giving Free Rides in This Town to Curb Drunk Drivinglast_img read more

Nativos Next Generation Ad Server and Monetization Platform Gains Wide Adoption with

first_imgPremium Publishers Including the Globe and Mail, Tribune Publishing, Lonely Planet and the Philadelphia Inquirer Choose Nativo to Accelerate Their Adoption of Next Generation Creative Formats and Boost Go-To-Market SpeedNativo, the leading monetization platform for premium publishers, continues to quickly expand its footprint with publishers looking to drive their bottom-line and explore alternative best-in-class solutions to Google Ad Manager. Nativo’s platform now serves more than 500 major publishers across the US and UK, including The Globe and Mail, Tribune Publishing, Lonely Planet and The Philadelphia Inquirer. With Lonely Planet, Nativo’s platform helped support sponsored content volume growth by as much as 300%.Nativo’s next generation ad server and monetization platform allows premium publishers to easily adopt new high-impact formats and accelerate speed to market with innovative advertising solutions. More specifically, Nativo’s key ad serving capabilities bring publishers the following unique benefits:Comprehensive support across all digital advertising formats. Includes in-feed display, scroll-to-play video, click-to-play video, outstream video, sponsored content articles (exclusive to Nativo), and traditional display.High-speed ad serving. Low latency allows publishers to accelerate page loads with reduced discrepancies.Flexible holistic auction across direct sold campaigns and third-party monetization, including unique demand exclusively sourced by Nativo. Enables publishers to maximize yield across all demand sources.Complete inventory control. Full control over auction settings such as demand prioritization, price floors, and blocklists allow publishers to achieve their unique business objectives.In-depth health reporting and insights. Advanced auction analytics give full transparency across direct sold campaigns and third-party demand, to help publishers optimize supply and monetization strategies.Marketing Technology News: True Influence Hires Data Strategist and Marketing Technology Visionary Ray Estevez as Chief Data OfficerPublisher testimonials for Nativo’s premium ad serving and monetization platform:Robin Gruen, VP, Creative & Strategy at Studio 1847, a Tribune Publishing Company – “Our partnership with Nativo has enabled us to provide deeper and smarter metrics for our native advertising clients. We are seeing great success with this platform.”Tracy Day, Managing Director, Creative Studio and Ad Innovation at The Globe and Mail – “Nativo’s ability to manage the complexities of branded content executions simultaneously across owned and operated sites as well as our Alliance publisher partners is a huge differentiator from alternative solutions in the market. Not only are we able to easily scale sponsored content ads across multiple Globe and Mail digital properties, but also seamlessly offer our clients the additional reach of our Globe Alliance partners.”Lauren Amato, Director of Client Success at The Philadelphia Inquirer – “Nativo clearly designed their ad server with publishers’ unique business needs in mind. The platform’s advanced capabilities have allowed us to execute branded content campaigns with full control and visibility. For example, their MOAT integration and ability to track advanced analytics such as scroll depth and velocity have given us more insightful data to drive successful results and increase satisfaction with our advertisers.”Marketing Technology News: How Digital Can Save Brick-And-Mortar Retail with Customer Experience Objectives Nativo’s Next Generation Ad Server and Monetization Platform Gains Wide Adoption with Premium Publishers PRNewswireMay 28, 2019, 6:13 pmMay 28, 2019 digital advertising formatsGoogle Ad ManagerMarketing Technologymonetization platformNativoNewsTribune Publishing Previous ArticleGainsight Unveils the Customer Cloud, the Future of Customer Success TechnologyNext ArticleComcast Technology Solutions Announces New Global Ad Management Solution that Unifies Linear and Digital Workflowslast_img read more

Physicians graduated outside the US offer better care for Medicare patients with

first_img Source:https://www.massgeneral.org/about/pressrelease.aspx?id=2362 Reviewed by James Ives, M.Psych. (Editor)Feb 20 2019A study by a Massachusetts General Hospital (MGH) research team indicates that internal medicine physicians who are graduates of medical schools outside the U.S. care for Medicare patients with more complex medical needs than those cared for by graduates of American medical schools. Their report, published online in the Journal of General Internal Medicine, has implications for a potential impact of Federal immigration policies on access to care for Medicare patients and potentially for others.”International medical graduates represent almost one quarter of U.S. practicing physicians and a third of primary care physicians,” says McKinley Glover IV, MD, MHS, of the MGH Department of Radiology, lead and corresponding author of the report. “We know they are more likely than domestic graduates to practice in underserved and rural areas, and our study – suggesting they also care for sicker patients – adds important information.”Given the current nationwide shortage of primary care physicians and the number of international medical graduates who provide primary care services, the MGH team set out to improve understanding of the needs of the patients they serve. To do so they analyzed information from the Center for Medicare and Medicaid Services (CMS) Physician Compare database, which includes background information for physicians participating in Medicare. They included physicians listed as practicing internal medicine, excluding subspecialties, and determined whether they were graduates of domestic or international medical schools based on physician profiles on Doximity.Information on Medicare patients cared for by each physician was based on the CMS risk scores that are calculated for patients based on age, gender and previously documented health problems and reported in the CMS Provider Utilization and Payment Data File. A risk score of 1.0 would reflect a Medicare beneficiary predicted to have average health care costs, while a score of 1.5 would indicate a beneficiary whose costs would be expected to be 50 percent higher.Related Stories‘Medicare for All’ emerges as early divide in first democratic debateStudy estimates health care costs of uncontrolled asthma in the U.S. over next 20 yearsSocial Security error jeopardizes Medicare coverage for 250,000 seniorsAmong the almost 75,000 internal medicine physicians included in the study, 52 percent were graduates of domestic medical schools, 30 percent were international medical graduates, and the status for the other 18 percent was unknown. While the average risk score of all Medicare patients was 1.73, among patients of domestic graduates the average score was 1.45, while patients of international medical graduates had an average risk score of 1.94. After adjustment for several characteristics related to physicians and their practices, the average scores for Medicare patients cared for by international medical graduates remained significantly higher.Senior author Jason H. Wasfy, MD, MPhil, MGH Division of Cardiology, says, “Studies have shown that the U.S. health care system has been increasing its reliance on international medical graduates to counteract the growing physician shortage. Our findings add to previous literature by demonstrating that international medical graduates generally care for sicker Medicare beneficiaries. Although policies that restrict or discourage international medical graduates from entering and practicing in the U.S. probably would not have an impact on care for several years, there is a real concern about restrictive immigration policies reducing access to primary care for the sickest Americans.”last_img read more

Researchers uncover new brain mechanisms regulating body weight

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)May 2 2019Researchers at University of Gothenburg, Sweden, clarify the link between the molecule interleukine-6 (IL-6) in the brain and obesity. In experiments on rats and mice they show that the molecule does affect the risk of obesity, and also where this effect occurs in the brain.Interleukine-6 (IL-6) is a well-known pro- inflammatory molecule, and an integral element of body’s first line of defense during infection. Intriguingly, the brain may govern and utilize IL-6 differently from the rest of the body.Researchers led by the laboratory of Karolina Skibicka at the Sahlgrenska Academy,Sweden (Mishra et al Cell Reports, 2019: https://www.ncbi.nlm.nih.gov/pubmed/30865890), asked: what happens to IL-6 levels in the brain following a diet that leads to obesity?Rats and mice were offered a high-calorie palatable food – a mix of fat and sugar, in addition to their regular low-calorie diet – like many humans, rodents choose to overeat when presented with calorie dense foods.”What we found was that the rats and mice that became obese, had reduced IL-6, but only in one brain region, called Lateral Parabrachial Nucleus (lPBN)”, says Devesh Mishra, postdoctoral fellow leading the study.”To understand whether this reduction of IL-6 is a good or bad thing for the metabolic health of the rodents, we viro-genetically reduced IL-6 levels very selectively in the lPBN; this led to increased body weight and body fat, even in rodents fed a healthy diet”.Therefore, the researchers conclude that the reduced levels of lPBN IL-6 in obesity are problematic, and likely contribute to metabolic dysfunction and weight gain.Related StoriesNeural pathways explain the relationship between imagination and willingness to helpRepurposing a heart drug could increase survival rate of children with ependymomaNew therapy shows promise in preventing brain damage after traumatic brain injurySince body weight is a result of how much we eat i.e. energy intake and how much energy we use i.e. energy expenditure, weight gain can follow dysfunction of either one of these branches of energy balance.What makes local parabrachial nucleus-produced IL-6 extra important, the study found, is that it affects both branches simultaneously: it decreases food intake and increases energy expenditure, the latter by increasing brown fat activity, so body’s energy is utilized for heat generation or fat burning. Hence reduced levels of lPBN IL-6 disrupt the entire energy balance equation.These findings may be relevant not only for mice but also men, since an earlier study from University of Gothenburg, revealed that blood serum IL-6 levels in obese and overweight men are increased, yet brain IL-6 levels, measured in cerebrospinal fluid, are reduced.There is one unsolved piece of the puzzle in these new findings – researchers found that the obesity-associated reduction in IL-6 was only present in males. Female rats and mice had normal IL-6 levels. The Sahlgrenska team is now investigating why females are protected from the obesity-associated IL-6-driven dysfunction.Given that obesity is a major global disorder with 1.9 billion overweight individuals out of which 650 million are obese, new effective anti-obesity treatment are desperately needed to minimize the amount of personal and medical burden on individuals and overall our societies. On the scientific end, we think that IL-6 as a satiety mediating substance with a brain region specificity is an important discovery and can open new directions in the quest for more effective anti-obesity strategies. Source:https://sahlgrenska.gu.se/english/research/news-events/news-article//new-brain-mechanisms-regulating-body-weight-.cid1627241last_img read more